The method which I use to protect my files/folders:
1.) Make the desired file/folder
HIDDEN.
2.) Disable "
show hidden files/folders" option in
FOLDER OPTIONS.
3.) Disable
FOLDER OPTIONS either using registry editor or gpedit.msc
4.) Disable
Regedit using gpedit.msc.
5.) Rename gpedit.msc to something else, like regedit.msc
PS: 4 & 5 options r for those ppl, who know how to enable show all files/folders or Folder Options from regedit or gpedit.msc
Now only I know where my hidden file/folder situated and whenever I need them, simply I type their address in the address bar and press ENTER.