the same with me..i used the microsoft wireless optical desktop 700...the keyboard battery doesnt drained much..but it is the mouse which drained battery like anything...since I used the computer a lot and that means almost entire day

that could be a reason..I have since changed to a basic wired desktop set by microsoft...unless you r using your pc as HTPC or your pc cabinet is placed beyond the length of the cables, it doesnt make sense to go for a wireless one.
maybe there might be power saving options somewhere...in the settings of the wireless mouse drivers