What I did in my computer:
1.) Hide the file/folder, which u want to protect from others.
2.) Disable "Folder Options" from Tools menu using either registry or gpedit.msc, so that no one can enable "Show Hidden file/folders" option.
3.) Also disable regedit.exe from gpedit.msc, so that a smart user can't enable "show hidden files/folders" from registry
4.) And at last rename "gpedit.msc" to something else, like "regedit.msc" so that no one can enable again regedit.exe using gpedit.msc